Instruction at the station
of NoSA1
Info : Individual A has
47 chromosomes (one extra 21st chromosome). Some
characteristics
are short broad hands, short height, broad head, round face, large tongue,
slanting
eyes, and may have cognitive disabilities.
Name of disorder :__________________Gender of person :_________
Activity 1
1.
Identify chromosome 21 on the handout of karyotype
given
2.
Place the chromosome 21 cut given, on circle A of the
meiosis layout on the
manila card.
manila card.
3.
Draw the chromosome in step 2 in in the blank drawing
diagram given.
Non-disjunction of meiosis I
Non-disjunction of meiosis I
4.
Move chromosome from circle A to circle B1
5.
Draw the chromosome in B1 in the drawing diagram given
6.
Cut the chromosome to separate homologous chromosome
and move the cut
chromosome to circle C3 and C4
chromosome to circle C3 and C4
7.
Draw all the gametes
formed in the drawing diagram given
Nondisjunction of Meiosis II
Nondisjunction of Meiosis II
8. Repeat step 1-3
9. Cut the chromosome to separate homologous chromosome in
A
10. Move
the separated homologous chromosome into B1 and B2.
11. Draw
the diagram of B1 and B2
12. Move
chromosome in B1 to C1
13. Cut
sister chromatids in B2 and move the separated sister chromatids into C3 and
C4
C4
14. Draw
all the gamets formed.
Activity 2
1. Take one normal gamet from the box given
2. Place it D1 on the manila card
3. Choose one of the abnormal gamete (n-1)
for trisomy 21 in C1, C2,C3 or C4
4. Draw D2 and D3 your drawing diagram.
APENDIX 2
Instruction at the station
of NoSA2
Info :Individual B has 45
chromosomes(less one 21st chromosome). Some characteristics
are short
distance between eyed, large ears and contracted muscle.
Name of disorder :__________________Gender of person :________________
Activity 1
1.
Identify chromosome 21 on the handout of karyotype
given
2.
Place the chromosome 21 cut given, on circle A of the
meiosis layout on the manila card.
3.
Draw the chromosome in step 2, in the blank drawing
diagram given.
Non-disjunction of meiosis I
4.
Move chromosome from circle A to circle B1
5.
Draw the chromosome in B1 in the drawing diagram given
6.
Cut the chromosome to separate homologous chromosome
and move the cut chromosome to circle C3 and C4
7.
Draw all the gametes
formed in the drawing diagram given
Nondisjunction of Meiosis II
Nondisjunction of Meiosis II
8.
Repeat step 1-3
9.
Cut the chromosome to separate homologous chromosome in
A
10. Move
the separated homologous chromosome into B1 and B2.
11. Draw
the diagram of B1 and B2
12. Move
chromosome in B1 to C1
13. Cut
sister chromatids in B2 and move the separated sister chromatids into C3 and C4
14. Draw
all the gamets formed.
Activity 2
1. Take one normal gamet from the box given
2. Place it D1 on the manila card
3. Choose one of the abnormal gamete (n-1)
for trisomy 21 in C1, C2,C3 or C4
4. Draw D2 and D3 your drawing diagram.
Instruction at the station
of NoSA3
Info: Individual C has 47 (extra X chromosome);
Some characteristics are small
testes, female-like
breasts, sterility, female-like voice, and developmental
disabilities.
Name of disorder :__________________Gender of person :________________
Activity 1
1.
Identify sex chromosome on the handout of karyotype given
2.
Place the sex chromosome cut given, on circle A of the
meiosis layout on the manila card.
3.
Draw the chromosome in step 2, in the blank drawing
diagram given.
Non-disjunction
of meiosis I
4.
Move chromosome from circle A to circle B1
5.
Draw the chromosome in B1 in the drawing diagram given
6.
Cut the chromosome to separate homologous chromosome
and move the cut chromosome to circle C3 and C4
7.
Draw all the gametes
formed in the drawing diagram given
Nondisjunction
of Meiosis II
8.
Repeat step 1-3
9.
Cut the chromosome to separate homologous chromosome in
A
10. Move
the separated homologous chromosome into B1 and B2.
11. Draw
the diagram of B1 and B2
12. Move
chromosome in B1 to C1
13. Cut
sister chromatids in B2 and move the separated sister chromatids into C3 and C4
14. Draw
all the gamets formed.
Activity 2
1. Take one normal gamet from the box given
2. Place it D1 on the manila card
3. Choose one of the abnormal gamete
(n+1) in C1, C2,C3 or C4
4. Draw D2 and D3 your drawing diagram.
Instruction at the station
of NoSA4
Info: Individual D has 45 chromosomes (one of the
sex chromosomes is missing,
often classified
as X0); .Some characteristics are short stature, swelling, broad
chests, congenital heart disease,
low hairline, low set-ears and webbed neck
Name of disorder :__________________Gender of person :________________
Activity 1
1.
Identify sex chromosome
on the handout of karyotype given
2.
Place the sex chromosome cut given, on circle A of the
meiosis layout on the manila card.
3. Draw the chromosome in step 2 in the blank drawing
diagram given.
Non-disjunction of meiosis I
4.
Move chromosome from circle A to circle B1
5.
Draw the chromosome in B1 in the drawing diagram given
6.
Cut the chromosome to separate homologous chromosome
and move the cut chromosome to circle C3 and C4
7.
Draw all the gametes
formed in the drawing diagram given
Nondisjunction of Meiosis II
8.
Repeat step 1-3
9.
Cut the chromosome to separate homologous chromosome in
A
10. Move
the separated homologous chromosome into B1 and B2.
11. Draw
the diagram of B1 and B2
12. Move
chromosome in B1 to C1
13. Cut
sister chromatids in B2 and move the separated sister chromatids into C3 and C4
14. Draw
all the gamets formed.
Activity 2
1. Take one normal gamet from the box given
2. Place it D1 on the manila card
3. Choose one of the abnormal gamete (n-1)
for in C1, C2,C3 or C4
4. Draw D2 and D3 your drawing diagram.
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